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20 Medico-Legal J. 1 (1902-1903)

handle is hein.journals/medlejo20 and id is 1 raw text is: TUBERCULOSIS. ON THE RELATIONSHIP BETWEEN HUMAN AND BOVINE TUBERCULOSIS BY J. G. ADAMI, Al. D., OF MONTREAL, Professor of Pathology, McGill University; Pathologist to the Agricultural Department, Dominion of Canada. [Concluded from March Journal.] An almost equally striking distinction between humarr and bovine tuberculosis was brought to light by a feeding experiment with swine. Six young swine were fed daily for three months with the tubercular sputum of consumptive patients. Six other swine received bacilli of bovine tuber- culosis with their food daily for the same period. The ani- rmals that were fed with sputum remained healthy and grew lustily, whereas those that were fed with the bacilli of bovine tuberculosis soon became sickly, were stunted in their growth, and half of them died. After three months and a, half the surviving swine were killled and examined. Among the animals that had been fed with sputum no trace of tuber- culosis was found, except here and there little nodules in the lymphatic glands of the neck, and in one case a few gray nod- ules in the lungs. The animals, on the other hand, whichl had eaten bacilli of bovine tuberculosis had, without excep- tion (just as in the cattle experiment), severe tubercular dis- ease, especially tubercular infiltration of the greatly enlargedi lymphatic glands of the neck and of the mesenteric glands, and also extensive tuberculosis of the lungs and the spleen. The difference between human and bovine tuberculosis appeared not less strikingly in a similar experiment with ass- es, sheep and goats, into whose vascular systems the two.. kinds of tubercle-bacilli were injected. Our experiments, I must add, are not the only ones that have led to this result. If one studies the older literature of the subject, and collates the reports of the numerous experi- ments that were made in former times by Chauveau, Guenth- er and Harms, Bollinger, and others, who fed calves, swine